4-甲基苯亚磺酸钠的合成

Synthesis of sodium 4-methylbenzene sulfinate

摘要:

研究4-甲基苯磺酰氯为原料还原合成4-甲基苯亚磺酸钠的工艺，以紫外分光光度法分析产物的含量。工艺采用亚硫酸钠水溶液为底物，滴加4-甲基苯磺酰氯的二氯甲烷溶液，反应过程中同时滴加质量分数为10%氢氧化钠水溶液控制pH。最佳工艺条件为：原料配比n(4-甲基苯磺酰氯)/ n(亚硫酸钠)=1:1.09，反应温度为85℃，反应时间为1h，水与原料的质量比m(水)/ m(4-甲基苯磺酰氯)=10，pH=7.6，收率为89%。

Abstract:

The synthesis of sodium 4-methylbenzene sulfinate was investigated by using sodium sulfite deoxidization process from the starting material 4-methylbenzene sulfonyl chloride and the contents of product were analyzed by UV-spectrophotometric method. The aqueous sodium sulfite which used as substrate was added dichloromethane solution containing 4-methylbenzene sulfonyl chloride, at the same time , the pH was controlled by adding dropwise 10% sodium hydroxide solution in the reaction process. The optimun reaction conditions were shown as follows: n(4-methylbenzene sulfonyl chloride)/n( sodium sulfite)=1:1.09, reaction temperature 85℃, reaction time 1h, m(water)/m(4-methylbenzene sulfonyl chloride)=10, pH=7.6,with a yield of 89%.