甲醛异丁烯热缩合合成3-甲基-3-丁烯-1-醇的研究

Synthesis of 3-Methyl-3-buten-1-ol via Thermal Formaldehyde-Isobutene Condensation

摘要:

以甲醇为溶剂，甲醛溶液和异丁烯为原料，通过Ene反应路径在无催化剂条件下合成了3-甲基-3-丁烯-1-醇(MBOH)，系统考察了反应温度、反应压力、物料配比和反应时间对MBOH收率的影响。结果表明：一定的温度是保证该反应进行的前提，当反应温度超过498 K后，MBOH的收率下降；反应压力对反应起促进作用，压力越大，MBOH的收率越高。在最佳反应条件：n(异丁烯) : n(甲醛) = 9 : 1，反应温度为498 K，压力为11.0 MPa下，反应6 h后MBOH的收率可达到59.24% 。

Abstract:

Synthesis of 3-methyl-3-buten-1-ol (MBOH) from thermal condensation of isobutylene and formaldehyde with methanol as solution was studied in this paper. The effect of reaction parameters such as temperature, pressure, isobutene/formaldehyde molar ratio, and reaction time were investigated. The result revealed that the yield of MBOH increased with the temperature at first and then decreased while increased upon increasing of reaction pressure. Under optimum reaction condition of 498 K, 11.0 MPa, isobutene/formaldehyde molar ratio of 9:1 for 6 h, the yied of MBOH could reach 59.24%.