新型N-（2,5-二甲基吡咯）亮氨酸酯的合成及其热裂解行为

Synthesis and Pyrolytic Process of N-( 2,5-Dimethyl pyrrole) leucine anisyl ester

摘要:

分别以亮氨酸和2，5-己二酮为原料，通过Paal-Knorr反应合成了N-（2,5-二甲基吡咯）-亮氨酸，接着以DCC为缩合剂，DMAP为催化剂，使之和大茴香醇等多种香料醇进行缩合反应，得到7种新型的N-（2,5-二甲基吡咯）氨基酸酯。通过IR、1H NMR、13C NMR、HRMS等波谱方法对产物结构进行了确证。并研究了N-（2,5-二甲基）亮氨酸大茴香酯在300℃、600℃和900℃的热裂解行为，分析鉴定出了对甲氧基苯甲醇，苯甲醇，苯乙醇，苯甲醛，烷基取代吡啶，取代吡咯和辛醇等50多种裂解产物，其中含有多种致香物质，能够有效改善卷烟吸味，增强香气。

Abstract:

Using Leucine and 2,5- hexanedione via Paal-Knorr reaction to form N-(2,5-Dimethyl Pyrrole)-leucine. Then by using DCC as dehydration reagent, DMAP as catalyst, the pyrrole acid derivatives were esterified with different hydroxyl compounds to give new pyrrole esters. The structures of all the compounds were confirmed by IR, 1H NMR, 13C NMR, HRMS spectral analysis. The thermal cracking behavior of pyrrole ester was respectively studied at 300℃、600℃ and 900℃, and 50 kinds of thermolytic products containing various aromas were authenticated which can improve the tobacco’s taste and flavor.