聚丙烯酸对(TTCP MCPM β-TCP)系骨水泥理化性质的影响

The Impact of PAA on the Physical and Chemical Properties of (TTCP MCPM β-TCP) Bone Cement

摘要:

用聚丙烯酸(PAA)作为固化液，对磷酸四钙(TTCP) 一水磷酸二氢钙(MCPM) β-磷酸三钙(β-TCP)系骨水泥理化性质进行研究。结果表明，随着液固比(固化液体积mL/固相总质量g)增大，固化时间延长，液固比为1.0时，终凝时间达7min；抗压强度随液固比增大，先升高后降低，液固比为0.8时达到最大值20.86 MPa；随浸泡时间增加,降解率先增加后逐渐趋于稳定；X射线分析(XRD)结果显示，随液固比改变，固化反应结晶物有羟基磷灰石(HA)和二水磷酸氢钙(DCPD)相出现，晶相的差异造成骨水泥降解率不同。

Abstract:

The physical and chemical properties of Tetracalcium phosphate (TTCP) +Monocalcium phosphate monohydrate (MCPM) +β-Tricalaium phosphate (β-TCP) bone cements with polyacrylic acid (PAA) hardening liquid have been studied. The results showed that the increasing of the liquid to powder ratio caused an increase in the setting time of cements which allows the possibility for their control, the final setting time was 7min when the liquid to powder ratio was 1.0; Compressive strength was also influenced by the liquid to powder ratio, when the liquid to powder ratio was 0.8, it reached the maximum 20.86 MPa. The degradation rate guadully increased along increasing immersion time, then attained stable. From XRD phase analysis, it was found that Hydroxyapatite (HA) and Dicalcium phosphate dihydrate (DCPD) were created in the setting process, suggesting that the various crystal phase in bone cement resulted in different degradation rate.