新型异戊酰基呋喃木糖的合成及其卷烟加香效应

Synthesis of 1,2-O-Propylidene-3-O-Isovaleric Acyl -5-O-Benzoyl -a-D-Xylofuranose and its Flavoring in Cigarette

摘要:

以二环己基碳二亚胺（DCC）为缩水剂，在4-二甲氨基吡啶（4-DMAP）催化下合成了化合物1,2-O-异丙叉基-3-O-异戊酰基-5-O-肉桂酰基呋喃木糖，其结构经IR、1HNMR、MS得到验证，并进行了热裂解和卷烟加香试验。结果表明：①合成产物为目标产物；②温度对合成产物的热裂解产物种类和含量有较大影响，主要有呋喃衍生物、月桂烯、异戊酸等；③合成产物的用量为0.002%-0.003%时与烟香谐调，可以改善卷烟香气质，增加香气量，降低刺激性，改善余味。

Abstract:

The compound 1,2-O-propylidene-3-O-isovaleric acyl-5-O-benzoyl-?-D-xylofuranose was synthesized with 4-DMAP as catalyst and DCC as dehydration reagent. Its structure was confirmed by IR、1H NMR、MS spectra and elemental analysis. The pyrolysis of the precursor and the application of the compound in blended cigarette flavoring were studied as well. The results showed that: 1) The synthetic product was the target compound; 2) Temperature has great influence on the types and content of pyrolysis of the compound, which mainly were furan derivatives、myrcene、2-methyl-2-pentenoicacid and so on；3）When the dosage of the synthesized compound was 0.002%-0.003%, it was in harmony with tobacco, and it can improve aroma quality, enhance aroma quantity, reduce irritancy and improve aftertaste of cigarette smoke.