2，6-二叔丁基对仲丁基酚的合成

Synthesis of 4-(sec-butyl)-2,6-di-tert-butylphenol

摘要:

以磺酸阳离子树脂为催化剂，对仲丁基苯酚和异丁烯为原料合成2，6-二叔丁基对仲丁基酚。重点探讨了不同催化剂、反应温度、反应时间、物料比和催化剂的用量对反应结果的影响。 最优的反应条件是选用磺酸阳离子树脂为催化剂，催化剂的用量为3%-5%（质量比），对仲丁基苯酚与异丁烯摩尔比为1: 2，在反应温度90-100℃，反应压力0.15-0.2Mpa，反应4h，，选择性约为95%以上，精馏分离得到大于97.5%的2，6-二叔丁基对仲丁基酚，反应收率为95%以上。

Abstract:

4-(sec-butyl)-2,6-di-tert-butylphenol was synthesized from 4-(sec-butyl) phenol and isobutene using sulfuric resin as catalyst. The influence of the catalyst, reaction temperature, reaction time, material ratio and catalyst dosage on the yield of the product had been investigated. The optimal reaction condition was using sulfuric resin as catalyst, choosing the amount of catalyst for 3%~5% (quality ratio), the molar ratio was n(4-(sec-butyl) butylphenol):n(isobutene)=1:2, the reaction temperature 90~100℃, the reaction pressure 0.15 ~0.2Mpa, the reaction time 4 hours. Under the optimal reaction condition, the conversion was more than 90% and selectivity was more than 95%. More than 97.5% of the 4-(sec-butyl)-2,6-di-tert-butylphenol was obtained by distillation separation.