1-甲胺基-1-甲硫基-2-硝基乙烯的合成

Synthesis of 1-Methylamino-1-Methylthio-2-nitroethylene

摘要:

以微纳米碳酸钾为碱，硝基甲烷与异硫氰酸甲酯在无水乙醇中反应，得到的1-甲胺基-1-钾硫基-2-硝基乙烯在水溶液中与硫酸二甲酯反应得到1-甲胺基-1-甲硫基-2-硝基乙烯，总收率为86%。探讨了物料比、反应温度、反应时间对异硫氰酸甲酯转化率的影响。化合物的结构通过FTIR和1HNMR进行了表征。

Abstract:

Potassium salt of 1-methylamino-1-thio-2-nitroethylene was synthesized from nitromethane, methyl isothiocyanate in the presence of macronano-K2CO3 and then reacted with dimethyl sulfate in water to give 1-methylamino-1-methylthio-2-nitroethylene. The overall yield was 86%. The effects of molar ratio of raw material, reaction temperature and reaction time on conversion rate of methyl isothiocyanate were investigated. The target products were characterized by means of FTIR and 1HNMR.