复凝聚法制备明胶/ES香精微胶囊

Essence-loaded Gelatin-di(stearylamidoethyl) epoxypropyl ammonium acetate Microcapsules Prepared by Complex Coacervation

摘要:

以古龙香精为芯材，首次以明胶和柔软剂二硬脂酰胺乙基环氧丙基醋酸铵（ES）为壁材，在搅拌条件下，通过复凝聚方法制备了香精微胶囊。探讨了戊二醛用量、ES与明胶用量比及ES的质量浓度对香精微胶囊形态的影响。应用TEM、SEM和激光粒度分析仪对香精胶囊的粒子尺寸及分布、形态进行等了表征。结果表明，戊二醛用量为明胶质量的2.2倍、ES与明胶质量比为1：0.3、ES的质量浓度为1.5%时所制备的香精微胶囊形态规整、粒径分布较窄、干态粒径小于1μm。所制备的香精微胶囊具有良好的缓释性能，80℃烘干7h仍然具有较高的香精残余量。所制备的香精微胶囊的装载量为41.1%，包埋率高达95.3%。

Abstract:

Under stirring condition, the essence microcapsules were prepared through complex coacervation method by using gelatin and softener di(stearylamidoethyl) epoxypropyl ammonium acetate (ES) as wall materials for the first time. The effects of the dosage of glutaraldehyde, the mass ratio of gelatin to ES, and concentration of gelatin on the shape, size and distribution of microcapsules were studied and characterized by TEM, SEM and particle size analyzer. The results showed that essence microcapsules with regular spherical, uniform particle size distribution were obtained when the mass ratio of glutaraldehyde to gelatin and gelatin to ES were 2.2:1 and 1:0.3, respectively, and the concentration of ES was 1.5% wt%. And the mean size of dry essence microcapsules were less than 1μm. Slow-release performance test showed that the essence microcapsules had excellent slow-release performance. UV-Vis test showed that the essence-loading rate and encapsulation efficiency of cologne essence microcapsules were 41.1% and 95.3%, respectively.