镧三元配合物的合成及其抑菌活性

Synthesis and Antibacterial Activity of La Ternary Complexes

摘要:

在常温下，以乙醇为溶剂，用肉桂酸、8-羟基喹啉和七水合氯化镧反应合成了镧的三元配合物。对其进行络合滴定、摩尔电导率、元素分析、红外光谱、紫外光谱、热重-差热分析、氢谱等测试，推测其化学组成为LaL1(L2)2 •H2O（其中HL1为肉桂酸；HL2为8-羟基喹啉）。并对其进行大肠杆菌、金黄色葡萄球菌、白色葡萄球菌、枯草芽孢杆菌和藤黄微球菌抑菌性质的测试，结果表明：镧离子、8-羟基喹啉和配合物均有抑菌活性。配合物抑菌效果明显优于其配体。

Abstract:

In ethanol medium, one ternary complex of lanthanum was synthesized using cinnamic acid, 8-hydroxyquinoline and Lanthanum chloride heptahydrate at normal temperature. The complex was tested by EDTA titration, molar conductivity, elemental analysis, infrared spectra(IR), ultraviolet spectra(UV), DTA-TG, and 1HNMR spectra. The composition of the complex was confirmed to be LaL1(L2)2•H2O (HL1= cinnamic acid; HL2= 8-hydroxyquinoline). The antimicrobial properties of Escherichia coli, Staphylococcus aureus, Staphylococcus albus, Bacillus subtilis and Micrococcus luteus showed that: lanthanum ion, 8-hydroxyquinolin and complex had an antibacterial effect, but antibacterial effect of the complex was significantly superior to the ligands.