一种紫外线吸收剂的合成新方法

New Method for the Synthesis of an UV Absorber

摘要:

采用新方法合成了紫外线吸收剂苯基-(3,5-二叔丁基-4-羟基苄基)丙二酸二(1,2,2,6,6-五甲基-4-哌啶)酯。苯基丙二酸二乙酯和N-甲基-2,2,6,6-四甲基-4-哌啶醇在甲苯中微纳米碳酸钾催化下反应，得到苯基丙二酸二(1,2,2,6,6-五甲基哌啶醇)酯，然后在乙醇中与 4-羟基-3,5-二叔丁基苄基氯反应，得到目标产物，总收率为80%。化合物的结构通过1H NMR和13C NMR进行了表征。

Abstract:

New method for the synthesis of UV absorber bis-(1,2,2,6,6-tetramethyl-4- piperidinyl)ester phenyl-(3,5-di-tertbutyl -4-hydroxybenzyl)malonitic acid was developed. Bis-(1,2,2,6,6- pentamethyl-4-piperidinyl)ester phenylmalonic acid was synthesized from diethyl phenylmalonate and N-methyl-2,2,6,6-tetramethyl-4-piperidinol catalyzed by micronano-K2CO3 in toluene, and then it reacted with 4-hydroxy-3,5-di-t-butylbenzyl chloride catalyzed by micronano-K2CO3 in ethanol to give the target product. The influence factors were investigated. The optimized overall yield was 80 %. The target product was characterized by means of 1H NMR and 13C NMR.