壳聚糖基碘抑菌膜的制备与性质研究

Study on Preparation and Bacteriostasis Properties of Chitosan-based iodine Antimicrobial Membrane

摘要:

壳聚糖（CTS）和3-氯-2-羟丙基三甲基氯化铵（CTA）合成壳聚糖衍生物—季铵盐壳聚糖（HTCC），HTCC与聚乙烯醇（PVA）共混得季铵盐壳聚糖膜(HTCC-PVA)，将其浸没于一定浓度的碘溶液中得含碘季铵盐壳聚糖膜（HTCC-PVA-I2）。用IR光谱，SEM和XRD进行表征。碘含量分析表明：膜中HTCC质量分数越高其吸附碘量越大。抑菌性测试表明：HTCC-PVA-I2膜对大肠杆菌和金黄色葡萄球菌抑菌环直径分别为(23? ) mm和(28?) mm，均为高度敏感。

Abstract:

chitosan derivative—quaternary ammonium salt of chitosan (HTCC)was obtained by chitosan(CTS)with (3-chloro-2-hydroxypropyl)trimethyl ammonium chloride(CTA). Blend with polyvinyl alcohol(PVA)derivative to obtain quaternary chitosan membrane material(HTCC-PVA). The membrane material was immersed in a concentration of iodine solution prepared in quaternary chitosan film complex with iodine(HTCC-PVA-I2). Its structure was characterized by means of IR, SEM and XRD, etc．The analysis of iodine content shows that the higher mass fraction of HTCC in membrane material the more adsorption of iodine.The antimicrobial test results show that the antibacterial diameters of the HTCC-PVA-I2 membrane against E.coli and Staphylococcus aureus were ( 23?) mm and (28?) mm ,indicating its significant bacteriostasis degree.