[Fe(C7H5O3)(C9H6NO)2]三元配合物的合成及抑菌性能

Synthesis and Antibacterial Performance of a Ternary Complex of [Fe(C7H5O3)(C9H6NO)2]

摘要:

本文以水杨酸、8-羟基喹啉为配体与铁(Ⅲ)合成了三元配合物，用元素分析、红外光谱、紫外可见光谱、荧光光谱等手段对其进行表征，确定其化学组成为[Fe(C7H5O3)(C9H6NO)2]。其中水杨酸脱质子以羧酸根与Fe3+成键，酚羟基不参与配位，而8-羟基喹啉脱质子以酚羟基氧和杂环上的氮原子双齿配位，形成五元螯环。配合物在整个可见光区都有较强吸收，粉末及其浓溶液均呈黑色，稀溶液显紫色。以300 nm为激发波长时，三元配合物在409 nm处有较强的发射荧光。采用分光光度法研究其对大肠杆菌生长的作用，配合物摩尔浓度低于2 mmol/L时，促进大肠杆菌的生长，高于2 mmol/L时抑制其生长，浓度越大抑制作用越强，即配合物对大肠杆菌的生长具有双向生物效应。

Abstract:

In this paper a ternary complex was reported. The chemical composition of the complex was [Fe(C7H5O3)(C9H6NO)]2, which was determined by elemental analysis, fluorescence spectroscopy, UV-visible spectra and IR spectra analysis. In this reaction salicylic acid coordinated with Fe(III) ion by carboxylic ion, and the phenol hydroxyl did not participate. The oxygen atom and heterocyclic nitrogen atom of 8-hydroxyquinoline were bidentate-coordinated with Fe(III) ion, forming a pentaheterocyclic. Extended the absorption of the compex into the whole visible-light region, the color of its powder and the concentrated solution showed black, the diluted solution was purple. When the excitation wavelength was 300 nm, the ternary compound emitted a strong fluorescence at 409 nm. The inhibitory effect of the ternary complex on the growth of E. Coli was studied by using spectrophotometry. The result showed that the growth of E. Coli was promoted when the concentration of the ternary complex was lower than 2 mmolL-1, however it was inhibited when the concentration beyond 2 mmolL-1. And the more higher the concentration was, the more stronger inhibition was. That was to say the complex had a bidirectional biological effect on the growth of E. Coli.