多苯环树枝状化合物的合成及对荧光小分子荧光作用研究

Synthesis of Multi-benzene Dendritic Molecule and Fluorescence Effect Research it to Fluorophores

摘要:

以均苯四甲酸酐（PMDA）和二乙醇胺（DEA）为原料，制备均苯四甲酰四二乙醇胺（PTDA），用小分子荧光体3,5-二羟基苯甲酸（3,5-DAC）修饰PTDA，合成多苯环树枝状化合物（PTDA -3,5-DAC）。通过红外光谱、核磁共振表征了其结构。研究了PTDA -3,5-DAC与荧光小分子（曙红B、罗丹明B、亚甲基蓝和达旦黄）组成的能量转移体系中，荧光小分子荧光强度的变化。实验结果表明，合成PTDA -3,5-DAC的最佳条件：反应温度为160℃，反应时间为4 h，催化剂对甲苯磺酸用量为2.0%，反应程度为75.67%。PTDA -3,5-DAC作用于曙红B和亚甲基蓝的DMF溶液，荧光强度逐渐降低；作用于罗丹明B的DMF溶液，荧光强度先增大后减小；作用于达旦黄的DMF溶液，荧光强度有较小程度的增强。

Abstract:

Pyromellit-tetra-diethanol amine (PTDA) was synthesized with pyromellitic dianhydride (PMDA) and diethanol amine (DEA) as raw materials. Multi-benzene dendritic Molecul（PTDA-3,5-DAC）was prepared PTDA using 3,5-dihydroxybenzoic acid(3,5-DAC) modifying PTDA. Its structure was identified PTDA means of FTIR and NMR. In the energy transfer systems of PTDA-3,5-DAC and fluorophores (Eosin B, Rhodamine B, Titan yellow and Methylene blue), the changes of fluorescence intensity were studied. The results showed that the optimum conditions were determined as following: reaction temperature was 160 ℃, reaction time was 4 h, catalyst dosage was 2.0 %, catalyzer was toluene sulfonic acid. The extent of reaction is 75.67 %. The fluorescence of fluorophores decreased when PTDA-3,5-DAC was added into Eosin B' and Methylene blue' DMF solutions. The fluorescence of fluorophore increased then decreased when PTDA-3,5-DAC was added into Rhodamine B' DMF solution. The fluorescence of fluorophore lesser increased when PTDA-3,5-DAC was added into Titan yellow' DMF solution.