负载纳米银磺化聚醚砜超滤的制备及其抗菌性研究

Preparation and antibacterial study of sulfonated polysulfone ultrafiltration membrane with nanosilvers

摘要:

为了改善聚醚砜（PES）膜的抗污染性能，将PES磺化，通过磺酸基与Ag+的相互作用及维生素C的还原作用，将Ag负载在磺化聚醚砜（SPES）膜表面，制备了负载纳米银磺化超滤聚醚砜膜（SPES@Ag）。通过扫描电镜（SEM）、原子力显微镜（AFM）、X射线衍射（XRD）对SPES@Ag超滤膜进行了表征，并通过细胞吸附法进行了抗菌性测试。结果表明，纳米银的平均尺寸为120 nm，它的负载提高了超滤膜的抗菌性能，对大肠杆菌、假单胞菌和金黄色葡萄球菌的抗菌率分别达到了96.7%，98.3%，87.7%。此外，通量和截留率的测试的结果表明，SPES@Ag超滤膜的水通量为438.4 L/m2.h，对牛血清蛋白(BSA)的截留率达到94.5%。

Abstract:

In order to improve the anti-fouling property of PES membrane, the PES was first sulfonated, by using the interaction between the sulfonated groups and silver ions. Then, the nanosilvers were introduced onto the surface of sulfonated polyethersulfone (SPES) membranes by using vitamin C as reducing agent to fabricate the sulfonated polyethersulfone membranes with nanosilvers （SPES@Ag）. Characterization of the SPES@Ag membrane was carried out by scanning electron microscopy(SEM), atomic force microscope(AFM) and X-ray diffraction（XRD）, antibacterial performance was studied by viable cell attachment test as well. It is show that nanosilvers were successfully loaded onto the surface of SPES and the size of nanosilvers is about 120 nm. The SPES@Ag membrane showed excellent anti- fouling property. The antibacterial rate reached 96.7%，98.3%，87.7% for E.coli, P.aeruginosa and S.aureus respectively, The results of the flux and rejection tests are shown that fiux was 438.4 L/m2.h and the rejection of BSA reached 94.5%.