固体酸催化芳烃Friedel-Crafts酰基化反应的研究进展

The Progress of Friedel-Crafts Acylation of Arenes over Solid Acid Catalysts

摘要:

芳烃的Friedel-Crafts酰基化反应是制备芳香酮类化合物的重要方法。与传统的均相催化剂催化该反应相比，高效且绿色的固体酸催化剂的研究发展一直备受国内外关注。本文综述了沸石分子筛、杂多酸、固体超强酸以及金属-有机骨架材料这几种固体酸的研究进展。此外，针对不同反应的特点，有目的地设计具有特定酸性、稳定且高效的固体酸催化剂，实现工业化生产是今后酰基化反应的发展方向。

Abstract:

Friedel-Crafts acylation of arenes is an important method to prepare aromatic ketone compounds. Compared to the conventional homogeneous catalysts applied in this reaction, green and efficient solid acid catalysts always attract more attention at home and abroad. In this paper, the research progress of zeolites, heteropoly acids, solid super acids, metal oxides and metal-organic frameworks were summarized. In addition, considering the characteristics of the various reactions, purposeful designing the solid acid catalysts with adjustable acidity, stable structure and efficient activity for industrial-scale production is the prospective development direction of Friedel-Crafts acylation.