水性抗菌羟基丙烯酸树脂的制备及性能

Preparation and Properties of anti-Bacterial Waterborne Hydroxyl Polyacrylate

摘要:

以甲基丙烯酸甲酯（MMA）、丙烯酸丁酯(BA)、丙烯酸(AA)、丙烯酸羟丙酯(HPA)为单体，过氧化二苯甲酰（BPO）为引发剂，以乙醇为助溶剂，采用半连续溶液聚合法合成得到水性羟基丙烯酸树脂（hs-WA)，再用三乙胺（TEA）中和，最后引入季铵盐抗菌剂3-（甲氧基硅烷基）丙基二甲基十八烷基氯化铵（TSA)与hs-WA进行反应，合成得到水性抗菌羟基丙烯酸树脂(hs-WAT)。利用FTIR、1HNMR、接触角、SEM、TG和DSC对样品进行分析并采用菌落计数法和抑菌圈法对样品进行抗菌测试。结果表明：TSA与hs-WA发生了化学链接反应；引入TSA反应前后，树脂的表面形貌没有改变；水接触角从78.5o增大至87.5o，表面疏水性能增强；样品的分解温度范围为299℃～456℃之间，热稳定性增大;树脂Tg为8.3℃，聚合物链柔韧性增强。抗菌性能分析表明：当引入TSA的质量分数为4%（以树脂的固含量计）时，得到的hs-WAT样品膜对大肠杆菌（革兰氏阴性菌）以及金黄色葡萄球菌（革兰氏阳性菌）的杀灭率达99.9%以上，具有显著的抗菌效果，且没有抑菌圈的形成，证明TSA未发生迁移，样品膜的抗菌方式为非渗透性抗菌。

Abstract:

Waterborne hydroxyl polyacrylate(hs-WA) was synthesized by semi-continuous solution polymerization,with methyl methacrylate(MMA),butyl acrylate (BA), acrylicacid（AA）and hydroxypropyl acrylate（HPA）as comonomers, the benzoyl peroxide (BPO) as intiator，ethanol as co-solvent and triethylamine(TEA) as neutralizer.Then, the quaternary ammonium salt antibacterial agent 3-(methoxysilyl)propyldimethyloctadecyl ammonium chloride (TSA) was introducedand reacted with hs-WA to synthesize an antibacterial waterborne hydroxy polyacrylate (hs-WAT).The samples were characterized by FTIR, 1HNMR, contactangle, SEM, TG, andDSC.The antibacterial properties of the samples were tested by colony counting method and inhibition zone method.The test results were as follows: the TSA was demonstrated to have chemical linkage reaction with hs-WA;After the introduction of TSA and hs-WA reaction, the surface morphology of the resin has not changed; The water contact angle increased from 78.5o to 87.5o, which showed the improvement in surface hydrophobicity; The introduction of TSA enhanced the sample thermal stability with the decomposition temperature is between 299 °C and 456 °C ;The Tg of the resin decreased from 13.5 °C to 8.3 °C,causing the polymer chains become more flexible. Moreover,it was found thaths-WAT sample films with 4% TSA mass fraction(based on the solid content of the resin) showed higher than 99.9% effective against Gram-negative bacteria (E. coli) and Gram-positive bacteria (S.aureus)respectively and no inhibition zoneformed,which proved thatTSA did not migrate and hs-WAT conformed to non-permeable contact antibacterial mode.