光气检测用小分子荧光探针的研究进展

Study progress in small molecular fluorescence probes for phosgene

摘要:

光气因其剧毒性对社会公共安全和人类健康造成巨大威胁，对其实时监测、检测十分必要。荧光探针由于选择性好、灵敏度高、可实时监测、成本低、操作简单等优点已成为识别光气分子的有力工具。首先，综述了光气小分子荧光探针的研究进展；然后，以荧光分子的识别基团为分类标准，从设计思路和识别机理对各类荧光探针进行了系统的归纳和总结；最后，对光气小分子荧光探针进一步的发展方向及其所面临的挑战进行了展望。

Abstract:

Phosgene poses a great threat to public security and human health due to its lethal toxicity. Fluorescent probes have become powerful tools in the detection of phosgene owing to their good selectivity, high sensitivity, real-time monitoring, low cost and simple operation. Firstly, the research progress of small organic fluorescent probes for the recognition of phosgene in recent years is reviewed. Then, the design idea and recognition mechanism of different kinds of probes are summarized according to the recognition groups of fluorescent molecules. Finally, the future development of fluorescent probes for the detection of phosgene and their potential challenges are prospected.