柔性表面增强拉曼散射基底分析检测农残进展

Progress in detection of pesticide residues by flexible surface enhanced Raman scattering substrate analysis

摘要:

农药是用于抑制真菌、预防虫害和调节植物生长机制的药物，开展农药残留分析对促进农作产品可持续发展具有重要意义。表面增强拉曼光谱技术具有非侵入、灵敏度高和指纹识别等优点，借助优异等离子体性能的贵金属纳米材料作为基底，可对单组份或复杂多组分的痕量农药残留物进行分析检测。但这类具有较高表面能的纳米粒子极易发生团聚，为解决这一问题，国内外科研者提出引入空隙率大的纤维素、高聚物及碳材料来支撑和固定修饰表面提供光谱增强作用的贵金属纳米材料。本文重点综述了不同类型柔性SERS基底（纤维素、透明胶带型、高聚物、生物质材料、碳材料等）常用制备方法及应用，充分利用SERS的“指纹图谱”分析优势，介绍了柔性SERS基底应用于不同农药残留的最新研究进展。最后，对SERS技术发展和应用提出了亟待解决的问题。

Abstract:

Pesticides are used to inhibit fungi, prevent insect pests and regulate plant growth mechanism. the analysis of pesticide residues is of great significance to promote the sustainable development of agricultural products. Surface-enhanced Raman spectroscopy (SERS) has the advantages of non-invasion, high sensitivity and fingerprint recognition. Using precious metal nanomaterials with excellent plasma properties as the substrate, single-component or complex multi-component trace pesticide residues can be analyzed and detected. However, this kind of nanoparticles with high surface energy are easy to agglomerate, in order to solve this problem, researchers at home and abroad have proposed to introduce cellulose, polymers and carbon materials with large voids to support and fix the surface modified precious metal nanomaterials to provide spectral enhancement. In this paper, the common preparation methods and applications of different types of flexible SERS substrates (cellulose, transparent tape, polymers, biomass materials, carbon materials, etc.) were reviewed, and the latest research progress in the application of flexible SERS substrates to different pesticide residues was introduced by making full use of the advantages of SERS fingerprint analysis. Finally, the problems to be solved urgently for the development and application of SERS technology are put forward.