通过脱羧加成反应合成二苯并衍生物：β-酮酸的无催化剂曼尼希反应

The Synthesis of Dibenzo[b,f][1,4]oxazepine Derivatives via Decarboxylative Addition Reaction：A Catalyst-free Mannich Reaction of β-Keto Acids

摘要:

我们已经建立了一种有效且通用的无催化剂的反应路线，用于获得二苯并[b，f][1,4]氧氮杂卓衍生物，所得产品的收率从较好到优秀（高达90%）。该过程涉及β-酮酸和环亚胺的无催化剂脱羧加成反应。

Abstract:

We have established an effective and general catalyst-free strategy for accessing dibenzo[b,f][1,4]oxazepine derivatives and the yield of the products obtained were good to excellent (up to 90%). The process involves a catalyst-free decarboxylative addition reaction of β-keto acids and cyclic imines.