壳聚糖/β-甘油磷酸钠混合比对溶液-凝胶转变性能的影响

Effect of mixing ratio on the sol-gel transition of chitosan/sodium β-glycerophosphate system

摘要:

为了研究混合条件对壳聚糖/β-甘油磷酸钠(β-GP)溶液温敏性的影响。采用β-GP溶液(质量分数50%)缓慢加入壳聚糖溶液(质量分数2%)的方法将两者混合,通过离线流变表征混合过程溶液粘弹性的变化。研究发现：壳聚糖溶液/β-GP溶液体积混合比为8/2时,体系具有热致溶液-凝胶转变特性。β-GP溶液的进一步加入不改变凝胶转变温度,但是凝胶结构变疏松。温度是壳聚糖/β-GP体系性质的重要影响因素。4℃时,体系保持稳定溶液状态。25℃左右时,溶液在一定时间后形成弱凝胶。升温至30℃以上时,壳聚糖/β-GP溶液迅速发生溶液-凝胶转变。

Abstract:

In order to study the effect of mixing condition on the thermo-sensitivity of chitosan/ sodium β-glycerophosphate (β-GP) solutions. The β-GP solution (50 wt%) was added dropwise in the chitosan solution(2 wt%), and the viscoelastic properties of the solutions were studied by off-line rheology. It is found that the system has thermal induced sol - gel transition character when the volume ratio of chitosan solution/β-GP solution is 8/2. When more β-GP solution was added, the sol-gel transition temperatures of the chitosan/β-GP solutions are similar, but the gel structure loose. Temperature is the important influence factor for the chitosan/β-GP solution. The solution is stable at the temperature of 4 °C and forms weak gel at 25 °C after a certain time. When the temperature is above 30 °C, sol-gel transition occurs quickly.