酶/MOFs复合材料催化性能调控及应用

Regulation of catalytic performance and application of enzyme / MOFs composites

摘要:

金属有机框架（MOFs）具有比表面积大、设计性强和生物相容性等优良特性，可以作为固定化酶的理想载体，从而提高游离酶的稳定性和催化性能，许多酶/MOFs复合材料也显示出比游离酶更好的催化性能。因此，酶/MOFs复合材料已应用于生物传感、检测、催化等领域，已然成为传统催化剂的环保替代品。本文综述了酶在MOFs上的三种固定化方法（表面固定、孔封装和原位包埋法），重点介绍了四种影响酶/MOFs复合材料催化性能的因素及调控方法，对酶/MOFs复合材料在催化方面的应用也进行了总结，并对酶固定化的未来进行了展望。

Abstract:

Metal organic frameworks (MOFs) have excellent characteristics such as large specific surface area, good designability and biocompatibility, which can be used as ideal carriers of immobilized enzymes to improve the stability and catalytic performance of free enzymes. Many enzyme/MOFs composites show much better catalytic performance than free enzymes. Enzyme/MOFs composites have been widely reported to be used in biosensing, detection, catalysis and other fields, becoming an environmentally friendly substitute for traditional catalysts. This paper summarized three immobilization methods of enzyme on MOFs (Surface immobilization, Pore encapsulation and In-situ synthesis), and emphatically introduced four factors influencing the catalytic performance of enzyme/MOFs composites and the modulation methods. Finally, the application of enzyme/MOFs composites in catalysis is summarized and the future of enzyme immobilization is anticipated.