酚酸类化合物在化妆品中的研究进展

Advances in the application of phenolic acids in cosmetics

摘要:

简单介绍了酚酸类化合物的来源和生物活性,综述了酚酸类化合物作为一种天然化合物,通过清除自由基、抑制炎症反应、抑菌、抑制酪氨酸酶活性、加速分解肌肤中的晚期糖化终末产物等途径起到的美白淡斑、抗衰老、抗炎、屏障修护等多重护肤功效,并介绍了酚酸类化合物的安全性问题,提出了酚酸类化合物生物利用度低、低水溶性等实际应用问题,采用生物基纳米颗粒负载酚酸类化合物可使部分实际应用问题得到改善。最后阐述了目前酚酸类化合物在化妆品行业应用中存在的问题,以期为酚酸类化合物在护肤领域的应用提供参考。

Abstract:

The sources and bioactivities of phenolic acids are briefly introduced, and the multiple skin care effects of phenolic acids as a natural compound, such as whitening and blemish reduction, anti-ageing, anti-inflammation and barrier repair through scavenging free radicals, inhibiting inflammatory responses, antibacterial, inhibiting tyrosinase activity and accelerating the breakdown of late glycation end products in the skin, are reviewed, and the safety issues of phenolic acids are presented. The practical application problems of phenolic acid compounds such as low bioavailability and low water solubility are presented, and some of the practical application problems can be improved by using bio-based nanoparticles loaded with phenolic acid compounds. Finally, the current problems of phenolic acid compounds in the cosmetic industry are described, with a view to providing a reference for the application of phenolic acid compounds in skin care.