钒基催化剂催化苯羟基化制苯酚反应机理

Reaction mechanism of phenylhydroxylation to phenol catalyzed by vanadium-based catalysts

摘要:

苯羟基化制苯酚是C—H键向C—O键转变富有挑战性的课题之一。该文论述了钒基催化剂催化苯羟基化制苯酚反应机理的研究进展。以钒活性中心为主线，着重从自由基、非自由基和双活性催化机理三个方面进行详细分析归纳，同时分析中涵盖了此类催化剂高效性的本质和催化微环境的重要性。由于此类催化体系及催化机理能够为解决苯环上C—H键难活化和苯酚的深度氧化等科学问题提供理论指导。因此，很有必要聚焦经济与安全并存的苯酚合成方法，同时依托已有的催化反应机理，开发更稳定且高性能的催化剂，促进我国丰富的烃类有机化合物资源利用的原始创新。

Abstract:

Hydroxylation of benzene to phenol is one of the challenging topics for the transition from C—H bonds to C—O bonds. In this paper, the research progress of the reaction mechanism of benzene hydroxylation catalyzed by vanadium-based catalysts to phenol is discussed. Taking vanadium activity center as the main line, the paper focuses on the detailed analysis and summary of three aspects: free radical, non-radical mechanisms and dual-catalysis mechanism, and covers the nature of the high efficiency of such catalysts and the importance of catalytic microenvironment. Because such catalytic systems and catalytic mechanisms can provide theoretical guidance for solving scientific problems such as inert C—H bond on benzene rings and deep oxidation of phenol. Therefore, it is necessary to focus on phenol synthesis methods that coexist with economy and safety, and at the same time rely on the existing catalytic reaction mechanism to develop more stable and high-performance catalysts to promote the original innovation of abundant hydrocarbon organic compound resource utilization in China.