植物多糖与活性成分协同效应研究进展

Research progress on cooperative effects of plant polysaccharides and active ingredients

摘要:

植物多糖广泛存在于自然界中,具有多种生物活性,包括免疫调节、抗氧化、抗肿瘤等。由于其低毒性和易吸收等特点,是目前医药及食品科学领域研究的热点。然而,低活性阻碍了其广泛应用。植物多糖与活性成分发生协同反应,可通过多靶点、多途径发挥生物活性,达到1+1≥2的作用。近年来,关于多糖生物活性的研究日益增多,但有关多糖与活性成分协同效应的综述较少。本文对有关多糖协同效应的国内外研究报道进行了归纳,对多糖与活性成分在抗氧化、抑菌、降血糖、抗癌、抗肥胖、抑制肝损伤六个方面中所呈现出的协同效应和作用机制进行了综述,以期为进一步开展多糖与活性成分的协同效应研究提供参考。

Abstract:

Plant polysaccharides are widely present in nature and have various biological activities, including immune regulation, antioxidant, anti-tumor, etc. Due to its low toxicity and easy absorption, it’s currently a hot research topic in the fields of medicine and food science. However, low activity hinders its widespread application. The synergistic reaction between plant polysaccharides and active ingredients can exert their biological activity through multiple targets and pathways, achieving a 1+1 ≥ 2 effect. Recently, there has been an increasing amount of research on the biological activity of polysaccharides, but there is limited review on the cooperative effects of polysaccharides with other active ingredients. This article summarizes research reports on the cooperative effects of polysaccharides both domestically and internationally, and reviews the cooperative effects and mechanisms of polysaccharides and active ingredients in six aspects: antioxidant, antibacterial, hypoglycemic, anticancer, anti obesity, and liver injury inhibition. The aim is to provide reference for