超传导莲纤维基纳米医用敷料的构建和表征

Construction and characterization of lotus fibers-based nano-medical dressing with superconductivity

摘要:

为提高医用敷料对伤口渗液的传导性，以具有优良吸湿导湿性能的莲纤维为基材，采用静电纺丝技术制备莲纤维/聚乙烯吡咯烷酮（PVP）纳米医用敷料，并与纯PVP纳米医用敷料进行对比。通过测试强力、水蒸气透过率、SEM、接触角等对其性能和结构进行表征，结果表明，所制备的莲纤维基纳米医用敷料的纤维分布均匀，表面无串珠；同时呈现互连的多孔结构，纤维直径越小，孔隙率越高（最高可达72.39%）；当莲纤维含量为5.5%（以PVP的质量为基准，下同）时，医用敷料的吸液率为487.02%，接触角降低到32.6°，达到超润湿性；水蒸气透过率可达2396.38 g/（m2·24 h），具有超伤口渗液传导性。该敷料对金黄色葡萄球菌具有一定的抑制作用，为提高新型医用敷料的性能提供理论和实践基础。

Abstract:

In order to improve the conductivity of medical dressing to wound transudate, lotus fibers/polyvinylpyrrolidone (PVP) nano-medical dressing was prepared by electrospinning technology using lotus fibers with excellent hygroscopicity and water transport performance, and compared with pure PVP nano-medical dressing. The properties and structures were characterized by testing strength, water vapor permeability rate, SEM and contact angle, etc. The results showed that the fibers of the prepared lotus fibers-based nano-medical dressing were evenly distributed and there were no beads on the surfaces. At the same time, the dressing had an interconnected porous structure, and the smaller the fibers diameters, the higher the porosity (up to 72.39%); When the content of lotus fibers was 5.5%, the liquid absorption rate of medical dressing was 487.02% and the contact angle was reduced to 32.6°, showing that ultra-wettability was achieved; The water vapor permeability rate could reach 2396.38 g/ (m2·24 h), indicating that the dressing had superconductivity to wound transudate. Besides, the dressing had antibacterial effect on Staphylococcus aureus, which provided a theoretical and practical basis for improving the performance of the new medical dressing.