天然产物活性物质抗肺炎的机制及进展

Research progress on the anti-pneumonia mechanisms of natural products with bioactive compounds

摘要:

肺炎作为全球高发呼吸系统疾病,肺炎的治疗策略一般为根据其类型、严重程度来制定控制饮食、适度运动、服用药物等。其致病因素复杂且传统治疗面临耐药性挑战。越来越多的研究表明,天然产物因其具有天然多靶点作用及安全性的优势,成为抗肺炎研究的热点。本文系统综述了天然产物活性物质的抗肺炎活性成分(如黄酮类、生物碱、多糖及有机硫化物)及其作用机制,探讨其在肺炎治疗中的应用潜力,为抗肺炎功能性食品的研究与开发奠定理论基础。

Abstract:

Pneumonia, as a highly prevalent global respiratory disease, generally requires treatment strategies formulated based on its type and severity, including dietary control, moderate exercise, and medication administration. The pathogenic factors of pneumonia are complex, and traditional treatments face challenges of drug resistance. Increasing research indicates that natural products have become a research hotspot in anti-pneumonia studies due to their natural multi-target effects and safety advantages. This article systematically reviews the active anti-pneumonia components in natural products (such as flavonoids, alkaloids, polysaccharides, and organosulfur compounds) and their mechanisms of action, explores their potential applications in pneumonia treatment, and lays a theoretical foundation for the research and development of functional foods with anti-pneumonia properties.